Arum palaestinum as a Food-Medicine

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Arum palaestinum as a Food-Medicine

A numerous records and a vibrant future

  • PALAESTINE ARUM

exhibit toxicity consequently a ways constrained to most cancers cells. Future segment 1 and section two scientific trials are crucial to totally recognize 

pharmacokinetics in human beings and to doubtlessly display scientific efficacy in human populations

Arum palaestinum Boiss is a widely used botanical in Traditional Arabic Palestinian natural medicine, the place it has been used to give a boost to bones and deal with cancer, parasites, infections, and many different maladies. Recent work demonstrates anticarcinogenic motion each in vitro and in vivo, and that work is coupled with a proof-of-principle mechanism of motion statistics displaying induction of the pro-apoptotic protein, caspase-6. The information to date is strongest for an Arum palaestinum extract that has been fortified with isovanillin, linolenic acid, and β-sitosterol, parts that are endemic to a crude water extract of Arum palaestinum. Safety records concerning toxicity are encouraging. Acute dosing animal research and in vitro studies, which evaluate results on cancerous and wholesome cell lines, 

arum palaestinum

Physical traits and taxonomy


Arum Palaestinum Boiss. is a flowering perennial species inside the household Araceae, additionally recognised by means of its frequent identify as Solomon’s lily,1 and frequently referred to in literature as black calla lily.2 Arum Palaestinum’s membership in the large botanical household of Araceae is sizable from an ethnobotanical perspective, as this household is coming to be considered as a in particular prosperous supply of medicinal botanicals.3

Arum palaestinum is protected in the genus Arum L, alongside with Arum italicam Mill. (commonly acknowledged as Italian lords and ladies), and Arum maculatum L (known as cuckoo pint).4 Species of Arum have been in the Mediterranean place for millennia, and are represented in engraved drawings in the temple of Thutmose III in Karnak as flowers that have been added to Egypt from Canaan in 1447 BCE.5

Arum Palaestinum is recognizable by using its red-brown/purple spadix and spathe of darkish crimson. The association of its leaf blades speaks to a typically used, aptly descriptive title in Arabic that interprets to “elephant ear” ,5 whilst its seeds are identifiable by means of their shiny pink shade.

arum palaestinum

Arum palaestinum as a food-medicine


Arum palaestinum has an eclectic history as both a food and a medicine. As is often the case, its use does not fit neatly into one or either category exclusively, but rather reflects its wide use as a food-medicine. According to Yaniv,5 the de-stemmed leaves, cooked with lemon or sorrel, are considered a delicacy by Arabs, who also traditionally esteem the plant as a medicine for the treatment of cancer, for the killing of worms in animals and humans, as a means to strengthen bones, as a treatment for infections in open wounds, and as a treatment for kidney stones. Additional sources confirm its use as a traditional Arabic medicine in the treatment of cancer, internal bacterial infections, poisoning, and disorders of the circulatory system, and refer to Arum palaestinum as a botanical used in Traditional Arabic Palestinian herbal medicine.6,7, Arum palaestinum is revered as a treatment for skin sores, syphilis, rheumatism, tuberculosis, diarrhea, and stomach worms.5

The measurable anticarcinogenic effects of the fortified extract of Arum palaestinum are accompanied by an understood mechanism of action that could apply across multiple types of solid tumors. 

According to a 2008 ethnobotanical study of edible plants within 5 rural districts of the Palestinian Authority, where preservation of the traditional knowledge of wild edible plants would be expected to be best maintained, Arum palaestinum was identified as one of the species rated highest for its cultural importance, a reflection of the diversity of ways in which an item is used as a food (eg, a vegetable, an herbal tea), and was cited by over half of those surveyed as a wild plant used for a food purpose.8 Consistent with a combined food-medicine use, Arum palaestinum is described in this survey as a food that is prepared by the leaves boiled in water, fried in olive oil, garnished with lemon, and consumed because of the belief that the plant helps prevent colon cancer. Also, in terms of contemporary use as a Complementary/Alternative Medicine (CAM), a 2011 questionnaire administered to a Palestinian cohort of 372 patients with cancer found that 43.5% of the cohort reported use of Arum palaestinum, making the plant the most commonly used CAM therapy among the cohort.9

Materials and Methods

To identify phytochemicals in Arum palaestinum reported to exert anticarcinogenic action, the author conducted a review of the peer-reviewed literature, using PubMed Central (PMC) and PubMed and the following search terms: Arum palaestinum, black calla lily, cancer, ethnobotany, and Traditional Arabic Palestinian herbal medicine. The author also reviewed the recently published in vitro and in vivo literature related to the anticarcinogenic activity of an extract of Arum palaestinum fortified with isovanillin, linolenic acid, and β-sitosterol, constituents that are endemic to a crude water extract of Arum palaestinum. Finally, the author reviewed mechanism of action and safety data published to date.

Discussion

As reviewed above, Arum palaestinum has extensive historical use as a food-medicine, with one of the most extensive traditional uses being as an herbal medicine used to treat cancer. When individual chemical constituents from the major chemical categories of Arum palaestinum are surveyed and connected to published literature, it is seen that a substantial number of the phytochemicals in Arum palaestinum show anticarcinogenic activity in their own right. Moreover, an extract of Arum palaestinum fortified with isovanillin, linolenic acid, and β-sitosterol shows very promising action against prostate cancer cells in vitro and in a mouse model. The anticancer potential of Arum palaestinum, combined with other emerging areas of therapeutic interest, such as preliminary evidence suggesting potential antinociceptive properties,47 portends an exciting future in the research of this botanical with an already rich ethnobotanical past.

References

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